Mutations in genes governing an important cell-signaling pathway influence human longevity, scientists at Albert Einstein College of Medicine have found. Their research is described in the March 4 issue of the Proceedings of the National Academy of Sciences. The report is the latest finding in the Einstein researchers’ ongoing search for genetic clues to longevity, a study that has recruited more than 450 Ashkenazi (Eastern European) Jews between the ages of 95 and 110.
In discovering the genes responsible for storing fat in cells, scientists at Albert Einstein College of Medicine have answered one of biology’s most fundamental questions. Their findings, which appear in the December 17 to 21 “Early Edition” online issue of the Proceedings of the National Academy of Sciences, could lead to new strategies for treating obesity and the diseases associated with it.
A gene variant linked to living a very long life—to 90 and beyond—also serves to help very old people think clearly and retain their memories, according to new research by scientists at the Albert Einstein College of Medicine of Yeshiva University. Their findings are published in the December 26, 2006 issue of Neurology.
Researchers at the Albert Einstein College of Medicine and colleagues have discovered that a gene mutation helps people live exceptionally long lives and apparently can be passed from one generation to the next. The scientists, led by Dr. Nir Barzilai, director of the Institute for Aging Research at Einstein, report their findings in the October 15, 2003 issue of the Journal of the American Medical Association (JAMA).